Genetic Methylation Testing: Unlocking Personalized Health Insights
- Oct 30, 2024
- 2 min read

Genetic methylation testing provides insight into how your body manages essential biochemical processes, particularly methylation. Methylation is crucial for DNA repair, detoxification, and cellular health. This type of testing identifies genetic variations, known as single nucleotide polymorphisms (SNPs), in specific genes associated with methylation, giving you a personalized look at your genetic blueprint.
Key Methylation Genes and Their Roles
Testing often focuses on specific genes with important roles in methylation, such as:
1. MTHFR (Methylenetetrahydrofolate Reductase) - Supports folate metabolism, affecting homocysteine levels and heart health.
2. MTR (Methionine Synthase) - Involved in homocysteine to methionine conversion, important for nervous system function.
3. MTRR (Methionine Synthase Reductase) - Helps regenerate vitamin B12 for DNA synthesis and repair.
4. COMT (Catechol-O-Methyltransferase) - Breaks down dopamine and influences stress response, mental health, and estrogen metabolism.
Who Can Benefit from Methylation Testing?
Methylation testing can provide valuable insights for those with fatigue, cardiovascular concerns, mood disorders, or individuals seeking a proactive approach to health. Health professionals can use test results to guide customized nutrition, lifestyle, and supplement plans.
What You’ll Learn from Genetic Methylation Testing
The test results reveal genetic predispositions impacting methylation, helping you make informed lifestyle adjustments to optimize your health. Personalized insights can help with understanding factors such as detoxification ability, inflammation risks, and nutrient processing, enabling precise recommendations for diet and supplementation.
Testing Options and Pricing
1. 3X4 Genetics Testing
• Our 3X4 Testing includes a comprehensive profile that examines multiple SNPs beyond methylation, covering additional aspects of metabolism, inflammation, and fitness. This test provides detailed insights into over 36 metabolic pathways, making it a robust option for those looking for an in-depth health analysis. There are over 157 SNPs across various genes, including those related to methylation, to provide an expanded view of genetic health influences.
2. 10X Health System Test
• Recently highlighted on Joe Rogan’s podcast by Gary Brecka, this test offers a focused panel on four methylation-related genes at approximately $600.
Using insights from tests like 3X4, you’ll be equipped with knowledge to address your unique health needs. This level of personalized data empowers you to work with a healthcare provider to make changes for a healthier future.
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